3) In the subsection "Effect of Non-Dihydropyridine CCBs: Verapamil," ascending aortic growth in verapamil-treated MFS mice did not "closely parallel" that in amlodipine-treated mice.
With respect to the second point, i.e. to clarify why we decided not to use a degree-preserving model, we have included two new paragraphs to the end of the subsection "Effect of different constraints on the generation of random networks" in Materials and methods to better justify the null model used and to clarify the connections between BQS and previous works on degree-preserving models.
A possibility for why vRNA and cRNA syntheses cannot be distinguished each other in infected cells had already been explained in the Results section (subsection "Effect of IREF-2 on viral RNA synthesis in infected cells"), as follows: vRNA serves as a template for cRNA synthesis, and vice versa.
Thus, in the following subsection, an effect of the building will also be taken into account when estimating the water distribution and the gravity change.
In this subsection, the effect of regularization constraints is analyzed using a simulated low-light image with σ=5. Figure 3 shows the results of proposed method using various different regularization parameters to analyze the effect of each regularization constraint.
In this subsection, the effect of applied electric field on the extent of degradation of dielectrics surrounding the narrow channel based on C C bonds broken by PD pulses inside the narrow channel is studied.
In this subsection, the effect of inaccurate PLE values on positioning accuracy is examined and depicted in Figure 4. Throughout the simulation, the PLE values α1=3.5, α2=2.7, and α3=2.3 are used in the RSS-KPLE algorithm, whereas actual PLE values are α1=3.8, α2=3.0, and α3=2.6.
We added this part (subsection "The effect of conformational changes on binding affinity prediction accuracy" and Figure 4), providing comparisons with a large number of other methods (110 in total).
Comparison with existing methods have been added (as also asked by reviewer 1) and is reported in subsection "The effect of conformational changes on binding affinity prediction accuracy" and in Figure 4.
In the following two subsections, the effect of time-frequency averaging is analyzed from the MIMO radar perspective in two aspects, namely, the auto-term TFD enhancement over the cross-term TFD and the signal TFD enhancement over the noise.
The effect of width is studied in this subsection.
