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In this connection, it must be noted that cytotoxic effect of STS on normal cardiomyocytes [34] and hepatocytes [35] appeared to be a limiting factor in STS application for anti-tumor therapy.
Interestingly, 140 K solution totally abolished the effect of STS on all three caspases.
We examined the effect of STS on the expression levels of Bcl-2, Bcl-xL, Bak and Bax proteins.
To determine the effect of STS on cytochrome c release, cytosolic extracts were assessed by Western blotting.
The effect of STS on wheezing and overweight in children was estimated as unadjusted and adjusted odds ratios with 95% confidence intervals (CI).
We have studied the effect of STS on PMP and ion channels inhibitors on the activity of caspases in HeLa cells.
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Furthermore, we compared the effect of ST on lung tissue morphology between the fresh air, CS exposure, and ST treatment groups.
According to these recent studies, other biomarkers that can evaluate the effect of ST on targeting the treatment of COPD should be performed for the further studies.
Analogous to the enhancing effect of ST on apoptin phosphorylation in normal cells, we observed an enhancement of apoptin phosphorylation in tumor cells by BCA3.
Given the strong positive effect of ST on treatment retention found in earlier studies [ 37- 39], dropout is analyzed with both multilevel logistic regression and survival analysis (to account for development over time).
However the conclusion from our review [ 2], that any effect of ST on pancreatic cancer has not been clearly demonstrated, seems justified by the data whether or not results from this study are included.
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