Sentence examples for effect of ros on from inspiring English sources
SA and/or SNP treatment increased the activities of antioxidant enzymes and reduced the adverse effect of ROS on amylase activity under Fe deficiency stress.
One would postulate that an increased anti-oxidizing capability in WS MSCs could principally counteract the harmful effect of ROS on compromising the biomacromolecule machinery (i.e. DNA or protein) inside the cells.
The effect of ROS on MPYS function likely also depends on the levels of ROS.
A direct anti-microbial effect of ROS on D. dadantii is unlikely since Miguel et al. [46] showed that there was no such effect for host-produced H2O2 in potato and tobacco.
Nevertheless, a correlation between children with severe malarial anemia and enhanced innate production of ROS by granulocytes, is indicative of a possible negative effect of ROS on the host [45].
Metabolic changes observed in AML cell lines in response to BEZ/MPA treatment reflect the downstream effect of ROS on TCA cycle metabolites and on pyruvate and suggest that changes directly induced by ROS significantly contribute to the mechanism of action.
The phenotypic effect of Ro 31-8220 on a zebrafish embryo model is consistent with the beneficial effect of this inhibitor on the cardiac phenotype observed in a DM1 mouse model (37).
When the effect of Ro-61-8048 on the development of CNS inflammation in these animals was investigated (Table 2) a significant reduction in the severity of the neuroinflammation (2.792 ± 0.100) was detected compared with infected animals treated with diminazene aceturate alone (P = 0.0284, 3.458 ± 0.187) and those given diminazene aceturate and vehicle (P = 0.0385, 3.500 ± 0.228).
To verify the effect of Ro 31-8220 and GF 109203X on CELF1 protein levels in our patient cell model, we conducted western blot analysis on triplicate samples following compound treatment.
The rapid effect of Ro-31-8220 suggesthathat ERK8 acts relatively directly on GalNAc-T traffic.
> -wrap-foot> In vitro experiments to investigate the effects of Ro-61-8048 on T. b. brucei (427) showed that addition of the inhibitor to the culture medium in concentrations ranging from 50 μM to 12 pM had no demonstrable effect of trypanosome growth in culture.
