Sentence examples for effect of ri on from inspiring English sources

The effect of RI on exposure correlates with the severity of the impairment, i.e., the more severe the dysfunction, the greater the effect on drug exposure.

20 By using CLCr as a guide for dosing patients with MM who have RI, Chen and colleagues 14 studied the effect of RI on the pharmacokinetics of lenalidomide after a single 25-mg oral dose (patients aged 39-76 years) in patients without cancer.

This database can also be used to examine the effects of RI on drugs that are nonrenally cleared.

There was no effect (P>0.05) of RI on microbial N flow or on efficiency of microbial nitrogen synthesis but the flow of non-ammonia non-microbial N was reduced (P<0.05) with the 38 d compared to the 28 d RI treatment.

This paper attempts to fill this gap by designing a comprehensive analytical framework composed of the input-side, output-side, process-side and environment-side effects of RIs on scientific activities.

In BIRMA patients, we studied the potential effect of RI (GFR<60) on hemoglobinemia and found that RI was a risk factor for anaemia (OR=1.54, (1.11; 2.1.11.

The rationale was that the influence of Ri on Rj would be strongest if Rj is the only reaction consuming the intermediary metabolite produced by Ri.

We evaluated the effect of renal impairment (RI) on the pharmacokinetics of telavancin and hydroxypropylbetadex (excipient in the telavancin drug product).

☑ The effect of DDI, RI, and HI are evaluated during drug development.

Hence, it is important to explore the effects of renal impairment (RI) on novel antidiabetic medications such as exenatide.

The inhibitory effect of CHX on gene expression (Ri-CHX) at t = 4 and t = 6 hpi and the inhibitory effect of PAA on gene expression (Ri-PAA) at t = 6 hpi were calculated using the formula of Pfaffl et al.[ 27].