Sentence examples for effect of plc on from inspiring English sources

We analyzed the sphingomyelinase activity and the effect of PLC on TNF-α-stimulated HIMECs.

As shown in Figure 7b, L-aminocarnitine increased ROS production (P<0.05 vs. control) and prevented the effect of PLC on TNF-α-induced ROS generation (P<0.05).

Finally, L-aminocarnitine strongly increased leukocyte adhesion (P<0.01 vs. control; Figure 7c,d) and prevented the inhibitory effect of PLC on TNF-α-induced leukocyte adhesion (P<0.05).

Moreover, we could not exclude a positive effect of PLC on circulating bone marrow-derived endothelial/hematopoietic progenitor cells, which can be locally recruited and contributing to inflammation, as already reported for vascular diseases.

The return of sensitivity to the toxic action of PrP82 146 coincided with the return of PrPC to the surface of the neurones as shown in Figure 2. Since glimepiride activates an endogenous GPI-PLC [16], [17] the effects of PI-PLC on neuronal responses to PrP82 146 were also examined.

The effects of the PLC antagonist on the b-wave would then have to originate with the second order response and we provide support for this possibility by showing that YM298198, an antagonist of the PLC-coupled mGluR1 receptor, has a similar effect on b-wave amplitude.

Therefore, we tested the effect of ABO on PC-PLC level and activity in vivo.

The present work reports the first evidence on PC-PLC accumulation and association with HER2 on the plasma membrane of HER2-overexpressing breast cancer cells and on the effects of PC-PLC inhibition on HER2 internalization, degradation, and recycling and on cell proliferation after transient or continuous cell exposure to anti-HER2 monoclonal Abs, including trastuzumab.

Possible effects of PC-PLC inactivation on HER2 expression on plasma membrane were investigated on SKBr3 cells cultured in the presence of the PC-PLC inhibitor D609.

To investigate the effects of PC-PLC inhibition on HER2 expression on cell membrane, internalization, and recycling, CLSM analyses were performed on fixed and permeabilized SKBr3 cells after incubation in the presence of D609.

As PC-PLC involved in oxLDL-induced HUVEC apoptosis, which was significantly inhibited by ABO, we first tested the effect of ABO on the protein level of PC-PLC in cultured HUVECs and MS1 cells.