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The effect of pcs on the performances of k-NN classifier is well exploited in the proposed study using ranking and non-ranking procedures.
However, based on previous reports, the effect of PCS on kidney progression has not been demonstrated.
It provides more evidences about the toxic effect of PCS on clinical outcomes.
Thus, in this study, we further investigated the effect of PCS on clinical outcomes including kidney function progression, cardiovascular event, and all-cause mortality in a pre-ESRD cohort.
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The effect of PC on WI is found very little here again.
While the positive effects of PS on cognitive appraisals did not extend to the affective stress response directly or indirectly, the negative effect of PC on the affective stress response was fully mediated by the secondary self-confidence appraisal.
Next, we examined the effect of PC on cell proliferation using primary OA FLSs.
The downregulatory effect of PC on these genes indicates that PC may reverse the processes of terminal differentiation and biomineralization.
There is no significant effect of PC on normal Human Breast MCF 10A cells indicating its non-toxicity to normal cells.
An inhibitory effect of PC on the activation of the MAPkinases ERK and p38 have been previously described [ 11].
The inhibitory effect of PC on OA meniscal cell-mediated calcification was also examined using monolayer culture.
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