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These results provide new insights into the effect of maturation on the assembly of meniscus ECM, and enable the design of new meniscus repair strategies by modulating local ECM structure and mechanical behaviors.
Reduced access and imprecise substrate cleavage associated with impaired gate plug dynamics is directly illustrated by the effect of maturation in our work and could explain the overall reduction in Aβ levels upon PSEN1 mutation and the increase in the Aβ 42/40 ratio.
We studied the effect of maturation on contractile properties of tracheal smooth muscle from seventeen 2-wk-old swine (2ws) and fifteen 10-wk-old swine (10ws) in situ and in vitro.
Although we cannot completely rule out the effect of maturation and innate composition, we infer that this change is associated with training or practice.
To evaluate the global effect of maturation stage on gene expression variation, we performed a principal components (PCs) analysis.
However, the authors argue that the differences found probably were due to the effect of maturation, which made the tasks too easy for this particular age group.
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The probabilistic maturation reaction norm (PMRN) describes the 50% probability of maturation as a function of age and size (and potentially other traits affecting maturation) while controlling for the effect of growth on maturation.
There is a confounding between the effects of maturation and retest effects.
Table 2 Some pediatric challenges in functional imaging studies [28] Small patient numbers Limited normative data Child unfriendly environment (MRI) Acoustic noise Motion artifacts Effects of maturation Effects of sedation Limited cooperation Monitoring task performance Limited acquisition time .
The effects of maturation, room temperature, and immunization on the strength of correlation were investigated.
We focused on a high-risk cohort, assessed diabetes risk using robust measures of insulin sensitivity and secretion from the FSIVGTT to estimate β-cell function, controlled for the potential confounding effects of maturation and body composition, and used powerful statistical modeling techniques to account for the variance component across time.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com