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Third, the authors only considered the effect of LD on imputation efficiency.
To examine the effect of LD on the PCA, we investigated the effect of the parameter 'nsnpldregress', which changes the input to PCA to be the residual of a regression involving Nreg previous SNPs, according to physical location.
We investigated the effect of LD on the PC analyses by varying the number of preceding SNPs (Nreg) considered in a regression analysis to predict the genotypes for each SNP, and then performing PCA on the residuals of the regression analysis, as described previously [23].
Furthermore, the relationship later derived for the effect of LD on power follows directly from it.
In this study, we examined the effect of LD on the sensitivity of the Multifactor Dimensionality Reduction (MDR) software package.
We conclude that the effect of LD on period is at most partly dependent on FLC, and LD function must also influence the circadian clock independently of FLC.
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Effects of LD on M1 excitability in MP have not been described.
The effects of LD on non-proliferating and proliferating PBLs were examined.
The magnitude of the "rest" condition may have exceeded effects of LD on MT, therefore obscuring any possible effects of this intervention compared to EL.
Still, effects of LD on M1 excitability compared to exposure to environmental light exposure (EL) had not been previously described in patients with migraine (MP).
To further our knowledge about differences between CS and MP, regarding M1 excitability and effects of LD on M1 excitability, we opted for a novel approach by extending measurement conditions.
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