Sentence examples for effect of individual genes from inspiring English sources

Disruption or overexpression of targeted mouse genes has been a boon to understanding the effect of individual genes in mammalian physiology.

Indeed, CAD and MI are paradigms of complex disease, in which the effect of individual genes on the risk is anticipated to be weak [23], [24].

The complex nature of the human HLA region on chromosome 6, with the extraordinarily high LD between genes, has made it extremely difficult to elucidate the effect of individual genes for the risk of developing T1D.

Human intelligence is characterised by a high level of heritability [1], [2] but known genetic effects can account for very little of this [1] and it has been suggested that the effect of individual genes may be much smaller than previously assumed [3].

However, these associations between loci and fitness need more refining to validate the effect of individual genes.

We used a jackknife approach to examine the effect of individual genes of a given gene set on our results.

In [ 12], the potential effect of individual gene on the global dynamical network behavior is studied, by means of random gene perturbation and intervention.

The impact of polyploidy on the evolution of networks was considered to be much more important than the cumulative effect of individual gene duplications.

A transient transfection method with Smartpool siRNA mix (Dharmacon Technologies, Thermo Fisher Scientific, Lafayette, CO, USA) was used to test the effect of individual gene on cell proliferation.

As complex diseases are caused by the joint effects of multiple genes, while the effect of individual gene or SNP is modest, a method considering the joint effects of multiple SNPs can be more powerful than testing individual SNPs.

The effect of individual gene variants may be more precisely characterized by examining phenotypes closer to the biological activity of the gene in the context of PTSD [ 25, 26].