In one study by H. Lei and colleagues, resting-state fMRI was integrated with genetics to examine the effect of genetic variation of the MAOA gene on resting brain activity in healthy male adolescents.
Imaging genetics is a research methodology studying the effect of genetic variation on brain structure, function, behavior, and risk for psychopathology.
We explored the main effects of single SNPs and also the cumulative effect of genetic variation within the inflammation pathway on toxicity risk.
A recent effort to quantify the effect of genetic variation on gene expression found that SNPs and CNVs contribute 83.6% and 17.7% of the total variation found [16].
We estimated the effect of genetic variation on CHD, ischemic stroke and the composite end-point of CVD in two prospectively followed population cohorts.
As an increased VEGF expression has been associated with tumor progression and metastasis, these disease associations may well indirectly reflect the effect of genetic variation on VEGF levels.
It is essential to separate the true effect of genetic variation from other confounding factors, such as adaptation to different uses and geographical locations.
Recent studies have focused on mapping the functional domains of EIAV Rev (ERev) shown in Fig. 1 [26], [26] and determining the effect of genetic variation on Rev activity [24], [27].
