Sentence examples for effect of genetic mutations from inspiring English sources

However, drugs to counteract the effect of genetic mutations have not yet been found.

She did her master's degree research project at the Institute of Biochemistry and Biophysics (IBB), also in Warsaw, looking at the effect of genetic mutations on the function of an enzyme involved in the biosynthesis of heme, using Saccharomyces cerevisiae as a model organism.

This is especially important when investigating the effect of genetic mutations on environmental perturbations such as DR because lifespan extension by DR is not binary but instead a graded response.

This is in contrast to the effect of genetic mutations in the promoter region, which usually abort the binding sites of transcription factors.

Here we describe two methods (see Fig. 1 for a schematic of the methods) that utilise the aggregate effect of genetic mutations to study potential G × E in a more powerful and reliable way compared with the candidate-gene approach.

Our molecular understanding in this field now ranges from transcriptome profiles of innate and adaptive immune cells to epigenetic regulation of cytokine expression and the effect of genetic mutations on immune-mediated diseases.

The effect of genetic mutation in particular TFBSs on the methylation state of CpGis has recently been refined by Lienert et al. [ 27].

Vemurafenib is the latest so-called targeted therapy, which inhibits the effects of genetic mutations that spur tumor growth and spread.

How do the effects of genetic mutations percolate through the physiology and development, from the molecules they affect, to the traits, and trait combinations, which are selected?

AML is a cancer of the blood and bone marrow which results from the combined effects of genetic mutations, aberrant interactions in the microenvironment and altered networks of complex chemical reactions at the molecular and cellular level, some of which can be targeted with anti-neoplastic drugs called chemotherapy.

In the context of oncology, this predominantly means incorporating the effects of genetic mutations into predictions (point (ii) above).