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The goal of this step is only to narrow down the solution space and reduce the effect of futile cycles in the simulation of gene perturbation.
Similar(59)
Thus, there is a need to identify breast cancer patients who will benefit from specific adjuvant therapies, while sparing others from the side effects of futile treatment.
Frenzies of futile rage ravaging only oneself.
This knowledge can save a lot of futile work.
However, these strategies are rather inefficient, resulting in a large number of futile invasive procedures.
The avoidance of futile aggressive therapies prevents unnecessary treatment and improves quality of life.
Therefore, we are not merely speaking of futile treatment.
On the other hand, ineffective interventions may have apparent positive effects on surrogates (false-positive) leading to unnecessary confirmatory studies in which the true lack of efficacy is discovered after years of futile effort [ 1].
This relates to obtaining social acceptance, one of the criteria of futile life-prolonging treatments.
For 58% of consultants there was no formal institutional protocol for withdrawal of futile therapy.
In this context, the use of PET can significantly decrease the number of futile laparotomies [4].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com