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We now show a direct effect of fruitless on brain wiring: a functionally validated change in connectivity between identified neurons.
Although previous studies have demonstrated a cell-autonomous effect of fruitless on neuronal morphology (Kimura et al., 2005, 2008; Ito et al., 2012), we now demonstrate a difference in functional connectivity.
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Unfortunately, not all patients respond to all treatments, and the matter of selecting the optimal treatment for each patient is a key element in minimizing the number of fruitless treatments with unnecessary and harmful side effects, as well as improving survival.
The review points out that a blinkered obsession with increasing supply to lower house prices is fruitless: the cumulative effect of large-volume housebuilding on prices is negligible, and does very little to lower them.
After a series of fruitless negotiations, Moro was murdered.
After two years of fruitless struggle?
Nine months of fruitless searching have made that increasingly clear.
Other non-spring-ers, like Algeria, had already gone through their own cycles of fruitless revolt.
The years of fruitless protest and economic hardship have taken a toll.
Instead, up to 20,000 people convene every year for two weeks of fruitless discussions.
A new spasm of fruitless violence, perhaps even a third intifada, is possible.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com