Another interesting extension of the current research would be an analysis on the effect of patent expiry on therapeutic substitution.
Although Klok et.al [ 30] have already identified a positive effect of the patent expiry of branded omeprazole on therapeutic substitution within the PPI group, investigation in a larger number of drug classes would give a more general impression of the effect of patent expiries on therapeutic substitution.
Because the effect of removal of RTO expiry was amortized during the session, LE is not considered to be an aggressive method.
With sequestration upon us, and the labour market far from immune, combined with the depressive effect of the payrolls tax cut expiry, we envisage a period of much softer data and rising anxiety as we head towards the May 19 debt ceiling stand-off.
Patents on many lucrative drugs are on the verge of expiry.
As concerns the period of validity, many ordinances do not include a specific date of expiry.
There was a risk of expiry mainly for child blister packs for both MB and PB.
However, given the possible association of expiry by date of analysis with quality, we investigated the relationship between drug quality and other risk factors by recalculating their odds ratios (ORs) adjusting for expiry by date of analysis.
The concept of "expiry date" for PD after 5 or so years still seems viable among nephrologists.
For 260 deaths date of expiry was found to precede the date of recruitment; hence these subjects were excluded.
European-style options can only be exercised on the date of expiry or the last business day prior to expiry.
