We examined the effect of deletion of the C-terminus on TORC1-mediated localization of Cdc5.
This is the first study to find an additive effect of deletion of both HCRT and HCRT receptor bearing neurons in the pons.
We decided to measure the synthetic effect of deletion of MEC1 and expression of Rpn4* since Mec1 is the major checkpoint protein in S. cerevisiae [19], [31] [33].
Using a novel-object recognition test, we next investigated the effect of deletion of the Hb-egf gene on learning and memory performance.
The effect of deletion of FUN30 on growth minus uracil or survival in the presence of 5-FOA was less pronounced (not shown).
Two approaches were used to test the effect of deletion and mutation of amino acid residues A159 and K160 in the M protein on the replication, budding and release of IBV.
In each analysis, the effect of deletion length was statistically significant, with the ≤3% definition yielding slightly stronger effects than our original <5% definition, and the ≤1% definition yielding slightly weaker effects: partial eta = .41, p<.001, and.
To determine the effect of deletion of 5'HS5 on the three dimensional (3D) organization of the locus, 5'HS5 was flanked by loxP sites to enable Cre-mediated deletion of 5'HS5 (PACΔ1B).
Recent work by four independent laboratories has examined the effect of deletion of the ERAP1 gene in mice and concluded strong, epitope-dependent effects in antigenic presentation [24] [26], [40].
To investigate the contribution of these genes to cognitive symptoms observed in DM1 patients, we studied the effect of deletion of Six5, Dmpk and Mbnl1 on three separate behavioral tasks designed to test learning and memory, anxiety and motivation.
The lack of a dependable inducible knockout system in the P. falciparum system, combined with the haploid genome of asexual parasite stages makes it currently impossible to study the effect of deletion of essential genes, or those conferring a massive growth disadvantage.
