Sentence examples for effect of complement from inspiring English sources

Therefore, experiments were designed to test the effect of complement depletion on cerebral infarct volume in adult rats and cerebral atrophy in neonatal rats.

To explore the association between polymorphisms in the complement component 3 (C3) gene and age-related macular degeneration (AMD), and to investigate the modifying effect of complement factor H CFHH) Y402H, LOC387715 andsmokingmoking.

The present study investigated the effect of complement C5a blockade in preventing BBB damage and pituitary dysfunction during experimental sepsis.

Despite the presence of an extensive range of responses to complement activation in normal tissues, the effect of complement activation in neoplastic tissue is not well understood.

For that reason, we focused our attention on a direct effect of complement activation on tumor growth rather than on an indirect immunomodulatory effect.

As a limitation of the study, a direct causal effect of complement activation alone cannot be proven from the present data.

Additional studies were performed to determine the cytotoxic effect of complement-opsonized particles of A. blazei Murill against human tumor cells in culture.

In particular, we were focused on effects of complement concentrations and effector cells to target cells ratios (Fig. 4a, b).

Open image in new window Fig. 1 The complement cascade leading to formation of mark attack complex (MAC) and other alternate effects of complement activation (inflammation and clearance).

The neurotoxic effects of complement fragments have recently been studied and blocking C5a anaphylatoxin resulted in neuroprotective effects in CLP-induced septic animals [26].

In the absence of S. Typhi-specific antibody, the wild-type strains were completely resistant to the effects of complement.