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Of these, previously described genes like PIK3CA, CDKN2A, TP63, EGFR, CASP8, NFE2L2, and KRAS show more than twice cumulative effect of alteration while rest of the genes are altered at several folds higher cumulative frequency based on integrated analysis.
Ch'ng Sl, Cheah SH, Husain R & Duncan MT (1989): Effect of alteration of eating pattern on serum frutosamine: total protein ratio and glucose level.
The effect of alteration in both substrate and protein structure is under investigation, with the goal of understanding the effect of changes in protein motion and active site geometry on tunneling.
The effect of alteration on rock strength and particularly the relationships between specific chemical indices and the engineering parameters are determined using simple regression analysis.
Furthermore, the proposed measurement scheme includes a thermal repeat measurement to assess the effect of alteration upon the accuracy of the final paleointensity result.
The effect of alteration and weathering on rock matrix porosity and on the available pore space, which affects diffusivity, are discussed.
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The effect of alterations in the physical state of the membrane lipids on the ability of Acholeplasma laidlawii B to grow at various temperatures.
The molecular mechanisms underlying the effect of alterations in type I collagen on bone mechanical properties are unclear.
However, we feel that our findings demonstrate the importance of understanding the role of endogenous adenosine production and metabolism on pulmonary development, and the effect of alterations in disease processes such as BPD.
Here, we investigated the effect of alterations in loop-1, a stretch presumably essential for FXN function, on the conformational stability and dynamics of the native state.
An in vitro collagen gel system was used to determine the effect of alterations in cytoskeletal tensional homeostasis on gene expression in tendon cells.
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