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One of the biggest criticisms was that the study didn't actually measure the effect of exercise but the effect of advising and offering exercise.
Horvath et al.[ 37] reviewed the effect of advising high-risk pregnant women to take LC-PUFA supplementation on a number of pregnancy outcomes.
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Previous studies with a follow-up period of up to 12 weeks found favorable effects of advising the patient to stay active on pain intensity, functional status and sick leave compared to bed rest, although the effects were not consistent across studies [ 12].
Despite the promising effect of resveratrol, advising individuals with FA to indulge in red wine to improve white blood cell counts is probably counterproductive, given recent data on the involvement of the FA pathway in acetaldehyde toxicity (Langevin et al., 2011).
The perceived effect of the advised preventive actions on health status was sufficient.
Those trials should especially focus on the effects of theory-based intervention development, combined with the effect of tailored advise and feedback [ 17].
In our opinion, the protective effect of tamoxifen is advised for younger patients, especially in Asian patients who have a higher risk of fractures at a younger age.
The effect of public health messaging advising the public to stay home if sick is uncertain, as the proportion of hours lost was actually lower in the summer months of 2009 than for previous years.
The procedure of removing outliers which are outside the confidence interval of the pooled effect size is advised when a common effect size is assumed.
Adequate monitoring of side effects is advised when new anticoagulants (dabigatran, rivaroxaban) are used.
The patient was informed of possible adverse effects and advised to avoid pain-provoking activities for the rest of the day.
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