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In ER+, PI3K mutant breast cancer cells, this negative edge dampens (but does not block) ER signaling, and all four other pathways are active; yielding the collective effect of a significant proliferation propensity and lack of apoptosis propensity.
The effect of a significant increase in the proportion of organic agriculture on pest (sensu lato) populations at the landscape scale is unknown and will depend on both the production of propagules in organic fields and the risk of pest dispersal between fields.
This paper studies the effect of a significant parameter of LSP, the advancing direction of the laser scanning pattern, on the induced residual stress fields and the fatigue life of stainless steel 316L samples using experiments and 3D finite element analysis.
This may reflect a compounding effect of a significant positive association between geographic disjunction and population size in this species, or alternatively may indicate that geographic distances between disjunct populations are not large enough to have a significant impact on the behaviour of insect pollinators.
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Trade in Asia is now "seeing some effects of a significant slowing in economic activity in Europe," Glenn Stevens, the governor of the Reserve Bank of Australia, said in a statement.
Chemotherapy-induced peripheral neurotoxicity is a major clinical problem because it represents the dose-limiting side effects of a significant number of antineoplastic drugs.
This simplification procedure was repeated until all effects and interactions in the model were significant with the exception that nonsignificant effects remained in the model if they were dependent effects of a significant interaction.
In this case, effect of A and B was significant.
This was not the result of a significant effect of these mutations on mRNA expression levels (Fig. 2d).
However, a relatively small effect of lithium and a significant effect of valproate on irritability/hostility have been reported previously (Swann et al. 2002).
We found no effect of optimism, but a significant effect of the attribution: Internal attribution predicted an increase in feelings of success.
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