The peripheral analgesic effect may be mediated through the inhibition of cyclo-oxygenases and/or lipoxygenases (and other inflammatory mediators) [ 36].
This effect may be mediated by electron donors on the olefin or, more effectively, by an insulating function between the olefin and the inorganic ring.
This isoflurane postconditioning effect may be mediated by mitochondrial KATP channels and PKC.
This effect may be mediated by the escalation of the apoptotic cell death pathway in the immature animal.
Further studies indicated that the effect may be mediated, at least partly, by retinal pigment epithelial (RPE) cells, which function as important regulators for CNV development.
This effect may be mediated, in part, in male, but not in female rat, by effects of exercise on early pharmacokinetic contributions.
No evidence was recorded indicating that this effect may be mediated by a difference in offspring survival rate with regard to the sex of the fawns or associated with metabolic indicators in the hinds.
Taken together, our findings suggest that honokiol has an anti-lipogenic effect in hepatocytes, and this effect may be mediated by the LKB1 AMPK signaling pathway, which induces ACC phosphorylation and inhibits SREBP-1c maturation in hepatocytes.
This effect may be mediated via improved myocardial metabolism and enhanced reduced glutathione content.
Possible class effects of antibodies include: Opsonisation, agglutination, haemolysis, complement activation, mast cell degranulation, and neutralisation (though this class effect may be mediated by the Fab region rather than the Fc region).
This effect may be mediated through CREB pathway and subsequent modulation of glutamate receptor subunits expression.
