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(ii) The movement of any conveyance which is solely for the purpose of effecting its repair, reconstruction, rehabilitation, or storage.
These and other studies provide evidence for a role for both midkine and Ptn in ameliorating the effects or effecting repair after injury to nervous tissue.
To evaluate its effect in myocardial repair, we induced a myocardial infarction (MI) by coronary artery ligation and administered a single intramyocardial dose of pyrvinium.
In addition, we investigated its effect on DNA repair using our challenge assay.
In the present study, the increased acute phase proteins fibrinogen and ceruloplasmin were significantly decreased by the SPP and SPE treatment, which shows its effect in tissue repair.
We therefore examined its effects on repair of cartilage damage in a rat meniscal tear model of OA.
miR-182 plays an ontogenic role in ovarian cancer partly via its effects on repairing DNA double-strand breaks, its negative regulation of breast cancer 1 (BRCand and metastasis suppressor 1 (MTSS1), and its positive regulation of the oncogene high-mobility group AT-hook 2 (HMGA2).
Figure 9C shows that the kinase activity of ATR is essential for its effect on U/G-repair-induced mutagenesis and further corroborates the siATR knockdown, because ATR deficient in kinase activity does not rescue it.
Despite its beneficial effect in DNA repair, PARP-1 activation has been implicated in necrotic cell death.
It is more likely, therefore, that the role of BRCA1 in the initiation of cancer is a result of its effects on DNA repair and the maintenance of genomic integrity [ 51].
A fourth mechanism by which electromagnetic field is thought to have an effect on bone repair is its influence on increasing the rate of bone formation by osteoblasts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com