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However, this effect is not systematically required to trigger full CTL activation since ligands with high affinity for the TCR, such as can occur in the domain of xeno- and allo-reactive responses, are largely independent of co-receptor activity 23, 24.
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However, this effect was not systematically examined – only four of the eight participants were tested using both coil types.
However, in this case, effects are not systematically positive or significant, particularly for the overall group.
Significant line effects were not systematically distributed to high or low, and were more likely attributable to the random effects of inbreeding and genetic drift than to fitness effects of the deformity (Table 1).
Although these effects were not systematically measured, since they were not included in the initial study design, these reports suggest that the positive effects of acupuncture for patients with multiple sclerosis may go beyond the specific aspects of QOL measured.
Moreover, the reported side effects were not systematically confirmed by clinicians or compared with clinical records, and we lacked data on which side effects led to reduction of the dose.
As standardised evaluation of typical side effects was not systematically available in our patient's population (e.g. National Cancer Institute's Common Toxicity Criteria, NCI-CTC), the number of side effects experienced by patients was considered instead as a surrogate outcome for toxicity (summarised in a 4-point scale; 0, 1, 2 and 3 or more side effects).
Yet their performance is not systematically monitored.
However, this recommendation is not systematically followed.
This is not systematically offered by professionals".
The assumption, however, is not systematically verified.
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