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For a mixed-effects model, the overall treatment effect is calculated by combining the within-patient and between-patient estimates (weighted by the inverse of their variances) [ 18].
Such an effect is calculated by setting the final demands as follows: [ Δ D J Δ D N Δ D S ] ′ = [ − e e 0 ] ′. (9).
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Overall estimates of the treatment effect were calculated by using a fixed-effects model, and statistical heterogeneity was measured by using a standard chi-squared statistic.
The topographic effect was calculated by considering the bottom water temperature and the relief of the seafloor (Fig. 5).
The appliance effect was calculated by subtracting the changes due to growth (control group) from the treatment changes (Table 6).
Therefore, the percentage of cupric chelating effect was calculated by the following formula: Relative chelating effect % = A 485 A 520 max - A 485 A 520 A 485 A 520 max - A 485 A 520 min × 100%% (10).
The Payne effect was calculated by the difference between the elastic modulus at 0.18 degree strain and at 2 degree strain [ΔG′ = (G′@0.18 − G′@2.0)] in uncured and cured samples at 1 Hz and 100 °C (Figs. 8, 9).
The degree of toxin effect was calculated by expressing the remaining current after each drug exposure as a fraction of the current magnitude of the patch prior to the first drug exposure (i.e., fractional current remaining, If).
P-values for each effect were calculated by ANOVA.
Trends in the OR (gene dosage effect) were calculated by assigning ordinal values to the genotypes.
The matrix effect was calculated by dividing the signal of the MMRS by the signal of a standard solution in water at equivalent concentration.
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