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β-blockers used as migraine prophylactics probably exert their effect in the CNS [37].
The β-blockers used in migraine prophylaxis probably exert their effect in the CNS [37].
The high doses of verapamil (480 to 960 mg per day) needed in cluster headache prevention are most likely due to a need for the drug to exert an effect in the CNS.
These results support a new neuroprotective vaccine paradigm in which general (nonself-reactive) immune stimulation in the periphery can limit potentially deleterious microglial responses to a neuronal insult and exert a neurorestorative effect in the CNS.
These findings suggest that the concentration of Humanin might be insufficient to confer a protective effect in the CNS.
All the known effects for MLIF relate to immune cell targets (i.e., locomotion in monocytes, ROI synthesis in neutrophils) but very little is known on its effect in the CNS.
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It minimizes the problems of bias, noise and batch effects in the estimation of CNs.
The reorganization energies indicate that CN derivatives would enhance the electron mobility while introduction of OCH3 has no effect in the enhancement of electron mobility.
Although we found a higher percentage of significant QTL alleles with additive DT effect in CN-NAM (46%%) compared to US-NAM (32 %), no large additive effect was evident.
As in the CN subjects, the MRI-based method would minimize the effect of white matter uptake in this region in patients.
Secondly, by introducing the EKF with correlated noises (EKF-CN) and its information filter EIF-CN, the CKF-CN is embedded in the EIF-CN framework to get a cubature information filter with correlated noises (CIF-CN).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com