While not believed to have teratogenic effects, excessive caffeine intake may account for low birth weight in infants.
We hypothesized that, in line with all its reported adverse effects, excessive levels of C5a might greatly impair the adrenomedullary catecholamine production and/or their release during sepsis, which might result in septic shock.
The trial was interrupted by the ethics committee due to the adverse effects (excessive bleeding) observed in the placebo group during follow-up.
Because of its strong vasopressive effects, excessive vasoconstriction and a decrease in cardiac index are associated with bolus injection of terlipressin [ 3- 6].
Because of their potential harmful effects, excessive ROS must be promptly eliminated from the cells by a variety of antioxidant defence mechanisms, including important enzymes, such as superoxide dismutase (SOD), catalase, and various peroxidases.
Is it the wearing-down effect of excessive film violence and video games?
But the effect of excessive usage of young pitchers does not show up immediately.
It harnessed the impact of Rachel Carson's 1962 book Silent Spring, in which she had documented the catastrophic effect of excessive DDT, along with that of several other man-made environmental disasters in the US.
"Instead of condemning the unlawful killings by the security forces, which have seen the deaths of more than 40 people in the last three weeks, this statement in effect authorises excessive use of force against peaceful protesters".
