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However, by that criterion, the majority of patients in our case study would be considered to have experienced a "large effect" both by ES and SRM statistics.
Addition of yeast during infection exerts a beneficial effect both by reducing by 50% invasion by Salmonella and maintaining the barrier function of epithelial monolayer.
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One possible explanation is that the dose/response curve for leptin is intrinsically bathtub-shaped, with adverse effects mediated both by excess and by insufficient leptin stimulation.
This suppression is due to a dual effect of nAG both by decreasing collagen synthesis and by increasing collagen degradation.
The class of miRNAs are posttranscriptional regulators that mediate their physiological effects both by target mRNA degradation and translational inhibition [ 2].
In premenopausal women, cytotoxic therapy is thought to exert its effects both by direct tumour cell kill and by an endocrine mechanism secondary to suppression of ovarian function (Pagani et al, 1998).
Both combine semi-nudity and pseudo-existentialism to hopelessly kitsch effect; both were created by well-established artists long switched to autopilot.
They took advantage of a striking effect, elicited both by addictive drugs like morphine and by running: the animals learn to prefer a place they associate with feeling high.
This effect, mediated both by the hemichannel pore activity and the C-terminal domain, leads to ERK activation and attenuation of osteoblast cell death [ 182].
To do this, we evaluated the effects of both by changing both the connect position and the distance between the heads using constructs with full-length neck linkers.
Metformin, a biguanide compound, exerts its clinical effect by both reducing hepatic glucose output and by increasing insulin sensitivity.
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