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It has been demonstrated that ESAT6 is toxic for the tested animals; in addition, we have found (unpublished data) that this protein may have a negative effect at the stage of regeneration of transformed plants under in vitro conditions (causing various morphological abnormalities in regenerants).
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The decrease in T cell development in the thymus could be due to aging effects at the stage of commitment to lymphocytes.
In difference to the IÖW model, the model for Japan refrained from evaluating the regional economic effects at the stage of system manufacture, in order to simplify the comparative analysis.
Information effect shapes the process mainly at the early stage, experience effect at the intermediate stage, and externality effect at the late stage as depicted in Fig. 1.
Surprisingly, higher serum iron levels were associated with better ALSFRS-R and better forced vital capacity at diagnosis, suggesting the absence of deleterious effect at this stage of the disease.
aMarkers used in the genome scan Challenge-tested fry, full-sibs of the post-smolts used for the genome scan, were genotyped to investigate whether the QTL had the same effect at the fry stage as at the post-smolt stage, the disease causing mortalities at these two quite different life stages.
Under this multistage hypothesis, the results indicate that arsenic exerts a definite late stage effect though an additional effect at the initial stage cannot be ruled out.
Mechanical loading, such as weight-bearing and functional electrical stimulation (FES), is promising if applied during the early stage of SCI but its effect at the later stage is unknown, with minor or no bone benefits reported.
The increase in the dispersity index, leading to the bimodal molar mass distribution profile, suggests an autocatalytic hydrolysis effect at the early stage of the composting process, during which the bulk hydrolysis mechanism dominantly operates.
While Laves phases generally precipitate slowly during service and have a more significant strengthening effect at the late stage, the precipitation of the alternative M23C6 precipitates can be used to increase the initial strength of ferritic steel.
The observed pressure effect on the crystallization kinetics in the amorphous alloy, which cannot be interpreted by means of the pressure effect on atomic diffusion, may be well understood in terms of the volume change effect at the early stage of crystallization.
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CEO of Professional Science Editing for Scientists @ prosciediting.com