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We note that any broad-scale analysis of this sort is complicated by the overlap in information (collinearity) between alternative predictors such different environmental variables or environmental and behavioral-ecological determinants, and the cause - effect assumptions inherent in statistical modeling approaches.
Multiplicative effect assumptions have been found to be valid in cardiovascular diseases, which makes the IMPACT model plausible [ 1- 8, 12].
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Open image in new window Figure 6 Linear actuation effect assumption test.
The combined relative risk (RR) and the 95% confidence interval for the RR were estimated with a fixed effect assumption.
This discrepancy also appeared in results from GEE models in which we tested the common exposure effect assumption.
Our analysis made the same "transience of effect" assumption as the case-crossover design (Maclure and Mittleman 2000).
An animation depicting the predicted age-specific LTP pattern over 60 years given the cohort effect assumption may be found here [ 21].
On the other hand, our results support the protective effect assumption of magnesium and the mortality risk due to cardiovascular diseases (Rubenowitz et al. 1996, 2000).
This approach identified that 1-3 nℳ paclitaxel with 0.25 1.5 μℳ CYC3 inhibits growth more than expected under an additive effect assumption.
In model fitting, we assumed that the lead biomarker cognitive score association was the same across all cognitive tests (common exposure effect assumption).
If we found no significant variance of γ distribution, we used a study stratified Cox model under the fixed effect assumption.
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