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In order to confirm that the naked DNA had no adverse effect, a subset of animals was injected with saline only.
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In order to assess the inherent uncertainty around (point) estimates of total intervention costs and health effects, a subset of intervention strategies were entered into an analytical software package (MCLeague), which performs a probabilistic uncertainty analysis using Monte Carlo simulation (1,000 runs were made, using a truncated normal distribution).
Finally, to assess genotype-by-environment effects, a subset of more densely-collected (supplementary material Table S1) La Réunion samples were cultured at two additional temperatures (15°C and 25°C), and assayed as above.
For these reasons we cannot be certain of the size of the genetic effect until the entire gene has been extensively investigated by re-sequencing and identification of all potential functional variants; either there is a small effect across the entire sample (consistent with multiple additive genetic effects) or a large effect in a subset of samples (consistent with genetic heterogeneity).
These results suggest that the suppression of RSC phenotypes is not due to a global effect on gene expression but rather due to an effect at a subset of genes.
However, loss of FOXP1 was accompanied by low FOXP1 expression levels in all four cases, indicating that low FOXP1 expression may be result from a gene dosage effect in a subset of neuroblastoma.
The meta-analysis, however demonstrated a significantly larger placebo effect for a subset of 28 studies with a specific aim of investigating the placebo effect.
The drug did show an effect for a subset of children with higher I.Q.'s.
Arguably, Rob Ford has somehow achieved a similar effect with a subset of black voters in the city.
Arguably, Rob Ford has somehow achieved a similar effect with a subset of Black voters in the city.
Our study includes extensive experimental validation of detected CNVs, as well as analysis of the effect of a subset of randomly selected CNVs on gene expression.
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CEO of Professional Science Editing for Scientists @ prosciediting.com