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Despite indistinguishable chromatin features, we reveal through genomic editing the functional diversity of several GATA switch enhancers in which enhancers with opposing functions cooperate to coordinate transcription.
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TGD Wiki was further updated by editing the short functional description given for each gene.
KN- editing the manuscript.
Both the editing mechanism and the functional role of editing in the dinoflagellate mitochondrion remains unclear, however, the conservation of many editing sites throughout dinoflagellates indicates that it is a stable character of this group (Lin et al. 2008).
Precise and straightforward methods to edit the plant genome are much needed for functional genomics and crop improvement.
To investigate whether the tissue-specific A-to-I editing may disrupt the functional elements of ESE and ESS, we analyzed the edited and unedited exon sequences with the EditFunc web server using the programs ESEfinder [34] [35] and FAS-ESS [36].
The correspondence between the edited sites and functional sites is summarized in Figure 2. We compared the ligand-binding residues and the residues converted by RNA editing in RuBisCO, for which binding sites for a ligand analogue are known [ 26], and found that none of the residues at the ligand-binding sites are converted by RNA editing (Fig. 1A).
Twelve maxicircle transcripts undergo the post-transcriptional uridine (U) insertion/deletion RNA editing to create the functional open reading frames (ORFs) [2], [3].
Selfish as organelle RNA editing may seem, the functional implications in the cell are fascinating.
RN edited the article.
YC edited the manuscript.
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