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About the editing necessary in some of the stories.
45 Importantly, exon 27 skipping does not affect APOB48 expression, as the RNA editing necessary for APOB48 expression occurs in exon 26.
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The students take on the range of reporting and editing roles necessary to produce a newspaper.
That meant only minimal editing was necessary to address the breaking news and get the podcast out early.
From the description of the workflow and DTM products demonstrated in Figs. 2 and 3, it was realized that no manual DTM editing was necessary and obvious matching blunders were not observed in the final DTM.
Sequences were assembled and edited with Sequencher 4.8 and aligned with reference sequences obtained from Los Alamos HIV database using Bioedit 5.0.9 [73], with manual editing as necessary.
After manual inspection and editing where necessary, sequences were aligned using ClustalX [33]; the intron alignment was conducted by taking into account secondary structure following Goddard and Burt [6].
The LTR alignments were verified using ClustalX [ 15], after manual editing as necessary (see Supplemental data).
Alignment quality was assessed by first constructing Neighbour-Joining trees in ARB; some manual editing was necessary to ensure that all secondary structure motifs were properly aligned.
Artemis v.14 (http://www.sanger.ac.uk/resources/software/artemis/) was used to combine and inspect the results of the ORF finder and the associated BLASTP [ 45] results, while this software tool was also used for manual editing, where necessary, of the start codon of a predicted gene.
The authenticity and outline of each spot was validated by visual inspection and edited if necessary.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com