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Nucleotide bases of RNA editing events that correspond to these in the mNav genomic sequence were in bold.
Editing events are predominantly post-transcriptional and include nucleoside insertions and deletions, and base substitutions and modifications.
ADAR family of enzymes mediate adenosine to inosine changes in double-stranded RNAs, contributing the major form of RNA editing events in human cells (Nishikura, 2010).
Further characterization of the RNA editing events in HCC might help elucidate the pathogenesis of this disease (Li et al., 2013b).
We experimentally demonstrated the effects of several cross-tumor nonsynonymous RNA editing events on cell viability and provide the evidence that RNA editing could selectively affect drug sensitivity.
All types of editing events are modestly higher at P7, overlapping with only a fraction of the editing events in the adult testis.
Thus, editing events act to oppose or modulate the action of miRNAs.
Analysis of miRNA editing in the testis showed that most types of editing events were higher at P14 than P7.
Several editing events in miRNAs have been reported.
Number of editing events for each remaining edge.
Regulated editing events might be recruited for functional processes.
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