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In our book ["A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution"], Jennifer Doudna and I write about germline editing being an inevitable milestone that scientists are going to advance towards.
"He kept saying, 'I've got to get back and edit my movie.' I was like, 'Oh God, this is one of those actors who wants to be a director.' But we really hit it off, and it turned out later that he was in the middle of editing Being John Malkovich".
Faster internet connections and more powerful processors - both in data centres and home computers - will open the possibility of high-end applications, such as video editing, being run in the same way.
Previous authors in the field have suggested subjective metrics of success such as less than 30 seconds of human editing being required to correct errors in the structure [40], while Filippov and Nicklaus [28] propose measuring success by calculating a similarity metric between the machine-produced structure and the correct structure.
With the data presented here we believe the rapid evolution of proteins from extensively edited transcripts is a consequence of RNA editing being a diversifying, rather than a conservation/repair mechanism.
Since this SNP is also of the A-to-G type, there could be A-to-I RNA editing being responsible for some of the observed discrepancies, even though individuals with both alleles of the gene would be able to produce both isoforms without the need for editing.
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The editing is often awful.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com