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This program works by contrasting the predicted amino acid sequence to the possible states of a codon with/without RNA editing against a homologous amino acid site of the coding gene from which RNA editing has been experimentally determined or from organisms with lack of editing capability.
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His next film, The Great Moment, edited against his wishes, was his first pratfall.
His suit against Christopher Hanley and other producers complained that footage of "9/11 jumpers edited against pornography" and a juxtaposition of "the holiest city in Islam against mind-control" had been inserted into the film.
Each week this mountain of scripts would be added to in the rehearsal room, shot, edited against the clock on the day of transmission and then shown to an audience that was initially lukewarm but soon grew to love the show and give BBC2 audiences of eight to 10 million at its peak.
Originally almost eight hours long, Greed was edited against von Stroheim's wishes to about two-and-a-half hours.
The paper needs to be heavily edited against numerous typos (e.g. 'specie' throughout the text), as well as grammatical and stylistic errors (e.g., 'Theoretically, a practical implication could be...'...., on p. 8; an oxymoron).
Protection against both p-Tyr and m-Tyr incorporation at Phe codons appears critical in E. coli as the PheRS enzyme maintains high active-site selectivity against p-Tyr as well as post transfer editing activity against m-Tyr-tRNAPhe.
Only the strain encoding wild type PheRS retained post transfer editing activity against p-Tyr-tRNAPhe.
It allows scanning for candidate RNA editing sites against multiple references simultaneously and prepares a comparative output for user evaluation.
We first filtered the editing sites against the known sites in the NCBI dbSNP database (Build 135) to eliminate germline variants.
The most conclusive results from these mutants suggest the stabilization of editing levels against temperature by mutations that increase editing, such as the DCS zip and Loop/Dock > α/α' mutations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com