Sentence examples for editing activities from inspiring English sources

This could represent a regulatory mechanism that prevents aberrant editing activities by maintaining low concentrations of ADAR2 at its active site when there are limited editable substrates and yet maintaining a readily available pool of functional ADAR2 to cope with a sudden influx of substrates that need to be edited.

None of these studies proves that NgAgo has any genome editing activities.

This inspection should result in editing activities that bring the knowledge closer to what the user intended.

Matarese's editing activities require a deep understanding of research in a wide area of medicine; this requires her to keep up with what's being done in the field, she says, and her biochemistry and biology background is essential.

These observations are entirely consistent with the previously reported studies with tagged or truncated A3G [31], [31], and indicate that A3G containing the solubility enhancing mutations maintained virus inhibition and DNA editing activities in the context of the full-length protein.

Compared to our previous data, which showed that KREPA3 ZF mutation had no effect on in vitro editing activities but dramatically reduced the fully edited mRNAs level in vivo [49], we showed here that the defect in editing in vivo caused by KREPA3 ZF mutation results from an inhibition of editing progression.

The extent by which tRNA stimulates editing also dropped from 7 to 1.5 (Table 1), indicating that tRNA enhancement of the Y59T editing activity originates from the active post-transfer pathway.

In an earlier study, Covello and Gray [ 24] insightfully dissected the complex question into three parts: 1) the origin of RNA editing activity, 2) fixation of mutations at editable sites, and 3) maintenance of RNA editing activity.

Some researchers have suggested a hypothesis of genetic drift resulting in both the appearance of editing activity and fixation of mutations at editable sites [ 24- 26], with a possibility of natural selection maintaining RNA editing activity [ 24].

Although the literature indicates that the amino-terminal domain of A3G is without editing activity [30], [31], this doesn't formally preclude a weak-editing activity.

The amino acid editing activity of the IleRS may result from the incorrect products shuttling between the synthetic and editing active sites, which is reminiscent of the editing mechanism of DNA polymerases.