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(d) Corresponding ex vivo gamma camera image of tumour from (a) showing 131I-huA33 uptake in all macroscopic tumour but highest uptake in viable areas (blue box), lesser uptake in necrotic areas (white box), and no specific uptake in normal liver tissue (upper right edge of specimen).
Different specimen thicknesses and different tapping positions have significant effect on the repeatability of test results; it is recommended that using 4 cm thickness specimen and impacting on the edge of specimen to evaluate the degradation of asphalt mixture anti-freeze-thaw performance.
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The finite element analysis together with test results revealed that the crack was initiated at the edge of the specimen when the specimen thickness was less than 1.0 mm.
Concrete strain gages were installed on both compressive and tensile area of the center and the edges of specimens.
The stress distribution near the edge of the specimen and in the lower part of the specimen, including the initial fracturing area and healed plane, was influenced by the lower end cap of the experimental apparatus.
6.4% (13/204) of patients had positive BCS specimen margins (defined as tumor at inked edge of BCS specimen) and 4.4% (9/204) of patients had close margins (defined as tumor within 1 mm or less of inked edge but not at inked edge of BCS specimen).
During fatigue testing, damage starts at the outer edge of the specimen, and then develops towards the middle of the specimen.
In the low strain amplitude regime, the void on the edge of the specimen induced two times higher microplasticity compared to void inside the specimen.
7.1% (13/182) of patients with negative BCS specimen margins (defined as no tumor cells seen within 1 mm or less of inked edge of BCS specimen) had at least one re-resection margin containing additional disease.
Their tumors were small, they had wide margins (the space between the outermost precancerous cells and the edge of the specimen that was surgically removed), and they were of a low-grade, non-comedo type.
It gradually diverts the damage towards the edge of the specimen and causes premature fatigue failure.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com