Transformed aortic ECs divided faster and were able to grow in medium with a low concentration of FCS (0.5%) and without growth factors (heparin and ECGS) that does not support growth of non-transformed cells.
For simplicity, we assume ECs divide perpendicular to their long axis (Minc et al. 2011).
In order to directly test for significant differences of PRC vs PHC intrinsic functional connectivity between the anterior vs posterior and lateral vs medial EC, we divided the template EC ROI equally into four portions: anterior-lateral, anterior-medial, posterior-lateral and posterior-medial (see Figure 3A, right panel).
In a next step, to directly test for significant differences between anterior/posterior and lateral/medial regions of the EC, we divided the template EC ROI into four equally-sized sections along the longitudinal and horizontal (or transverse) plane, corresponding to coronal and sagittal cuts, respectively.
In the primate literature, both monkey and human, many authors tend to take it for granted that LEC means the laterally positioned part/half of the EC and MEC means that it is positioned medially, i.e. EC is divided into a lateral and a medial strip.
Samples of OC and EC were divided into groups on the basis of their CDRs as follows (OC/EC): CDR 0, non-demented (n = 9/9); CDR 0.5, at high risk of developing AD dementia (n = 14/9); and CDR 5, severe dementia (n = 9/9).
The EC is divided into superficial (I III) and deep layers (IV VI) that show differential anatomical and functional organization (Suzuki and Amaral, 1994; Witter and Amaral, 2004).
Each time the EC was divided in two halves: Once along the anteroposterior (septotemporal) axis, once along the mediolateral/proximodistal axis.
Consistent with our previous analyses for the EC, we divided the subiculum into four equal portions along the longitudinal (anterior vs posterior) and transverse (lateral ['proximal'] vs medial ['distal']) axis.
ECs are divided into two types.
