Instead of massively parallel sequencing of primary tumors to identify somatic mutations suitable for AF ascertainment an easier approach is plasma-Seq, as it is independent of pre-knowledge of somatic mutations.
Our conclusions differ with those reported previously because we obtained a higher-resolution dataset, we accounted for the fact that gene length and transcriptional frequency are not independent variables, and we accounted for several ascertainment biases that make cryptic transcription easier to detect in long, infrequently transcribed genes.
In contrast, ascertainment of calcium supplement usage may have less error, thus making it easier to detect an association with calcium supplement use, as we found in this study.
Rapid case ascertainment and random-digit-dialing systems are in place to ascertain cases and controls, respectively.
Not a single study has measured the duration of disease directly, as this would require an exhaustive ascertainment of incident cases as well as a follow-up to either death, which is easy to establish, or cure, which is more difficult to establish, while withholding treatment, at least for some time.
He suggested that randomized controlled trials of subjects failing to achieve control on MDI were needed to better understand which type 2 diabetic subjects are appropriate candidates for the approach, that ongoing ascertainment of cost-effectiveness will be important, and that the development of simple and easy-to-use pumps will be of great importance in allowing greater use of this technology.
The strengths of the study are its population-based design, a large study sample size, prospective data obtained via a face-to-face interview and complete cancer case ascertainment through a comprehensive nationwide cancer registry in a small city-state with a system for easy access to specialised medical care.
Later, he added, "Open hearings are more conducive to the ascertainment of truth".
Prompt ascertainment is crucial for the management of hyperammonemic infants.
The narrator is demoted to the basement to "assist in the assembly and assessment" of ascertainment files.
