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We observed a clear tendency toward early triggering of apoptosis only in cells overexpressing the mutated form P86L‐CALHM1 at 3 and 6 h (data not shown).
The serum stiffening effect was rather rapid (<1 h), compatible with a role in the early triggering of leukocyte sequestration in the microvasculature.
Strategies aimed at avoiding the early triggering of events that we have described might therefore improve ultimate outcomes by reducing the resultant stresses on the emergency and hospital services.
It is not easy to provide one specific mechanism explaining the early triggering of apoptosis in a certain percentage of blood monocytes that would confer protection in the enrolled population of septic patients.
The increase in risk was observed just one to six hours after exposure and seemed to be offset by a reduction in risk in the following days, consistent with exposure to heat leading to an early triggering of myocardial infarctions in highly vulnerable people who would otherwise have had a myocardial infarction some time later ("short term displacement").
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Both teams scored early, triggering a match of attacking intensity that was only settled in extra-time by a stupendous volley from the Argentine winger, Maxi Rodriguez.
The first critical recommendation for policy is that highest priority should be given to the planning and education required for the early triggering and high compliance implementation of network-based interventions such as social-distancing or closing schools, rather than for case-based interventions such as antiviral prophylaxis or household quarantine.
This creates acute laminitis, and we can see the early triggers of the disease; the changes as a result of the onset of the disease.
We have occasionally observed clay particles in water collected by the needle-sampler and have attributed their presence to migration of groundwater below the bottom of the hole or to an early trigger of the sampler.
To expand our knowledge of the early triggers of NEC we describe our efforts to investigate NEC pathogenesis at an early stage of disease.
Based on its rapid appearance, we suggest that SNAIL1 expression is one of the early triggers of Type II EMT.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com