The contribution of Pax8 to thyroid cell survival has been suggested by the analysis of the early steps of thyroid morphogenesis in Pax8 null embryos.
Embryoid bodies mimic the early steps of spontaneous cell differentiation and morphogenesis of the early embryos and are tractable models to study these processes (Coucouvanis and Martin, 1995; Capo-Chichi et al., 2005).
All muscle genes reflecting early steps of the myogenic program, including Capsulin, Tbx1, MyoR, Myf5, MyoD and desmin are expressed in the branchial arches following neural crest cell ablation in chick embryos, although their expression domains are altered [21], [27].
(A ) Early steps of PIC assembly.
The subintestinal plexus of the developing zebrafish embryo comprises vessels that vascularize the gut, liver and pancreas and, as such, represents an ideal model to investigate the early steps of organ-specific vessel formation.
The subintestinal plexus of the zebrafish embryo comprises vessels that vascularize the gut, liver and pancreas and, as such, represents an ideal model in which to investigate the early steps of organ-specific vessel formation.
The earliest steps of left right (LR) patterning in Xenopus embryos are driven by biased intracellular transport that ensures a consistently asymmetric localization of maternal ion channels and pumps in the first 2 4 blastomeres.
In this study, mouse embryonal carcinoma cells (line P19) have been employed to address the question of how such molecular diversification develops during the earliest steps of differentiation that take place in the early embryo.
The defects in endocardial behavior in tal1-deficient embryos originate during the earliest steps of endocardial morphogenesis: tal1-deficient endocardial cells fail to generate a cohesive monolayer at the midline and instead pack tightly together into a multi-layered aggregate.
To define the impact of AP-2ε on earlier steps of embryonic cartilage development, we used mesenchymal cells isolated from limb buds of E11.5 WT and Tfap2e−/− mouse embryos in high-density micromass cultures.
