Sentence examples for early step of human from inspiring English sources

Id-1 plays a role in the early step of human carcinogenesis, for example, in melanoma and cervical cancer, whereas id-1 expression is markedly different between in situ and invasive breast carcinoma (Lin et al, 2000; Polsky et al, 2001; Schindl et al, 2001).

Increased expression of fatty acid synthase has been associated with the early steps of human mammary carcinogenesis [ 32].

Cultures of differentiating pluripotent stem cells such as human embryonic stem cells (hESC) or human-induced pluripotent stem cells (Leist et al. 2008a; Thomson et al. 1998; Takahashi et al. 2007) offer unique possibilities of studying the very early steps of human development that lead to the formation of germ layers and primordial tissues.

The implications of pannexin-1 and purinergic receptors in the early steps of infection of human primary CD4+ T lymphocytes and macrophages have been confirmed by others.

In the early step of resection, the MRX complex and Sae2 (ortholog of human CtIP) endonuclease create short 3′ overhangs [ 84, 85].

Thus, it has been suggested that Id-1 is one of the early markers in pancreatic malignant transformation and that it may contribute to the early step carcinogenesis of human pancreatic cancer.

We have shown that soluble rIDE enhances VZV infectivity and cell-to-cell spread in human melanoma cells at an early step of virus infection.

To determine which pathways govern the early steps of CIN in human carcinogenesis, a comparison of these models to chromosome alterations in tumor samples might yield important clues.

Besides genetically modified mice and ex vivo heart explants, ESCs provide a cellular model to study the early steps of valve development and might constitute a human therapeutic cell source for decellularized tissue-engineered valves.

Meanwhile, a study focusing on the early steps of HIV-1 infection revealed >200 genes in human 293T cells that may facilitate HIV infection.

Proteins are identified that underlie the early commitment steps of human hematopoietic stem cell differentiation.