If π is merely capturing net duration effects then we would expect to find a stepwise remittance gradient, with Early Exiles remitting the least because they have been in the US the longest, and New Cubans remitting the most because they are the most recent arrivals.
However, in contrast to early (relapsing-remitting) MS, the further inflammatory reaction in progressive MS seems to be compartmentalized within the CNS [24].
In early and remitting EAE, upregulated GFAP and astrocytic endfoot water channel aquaporin 4 (AQP4) enclosed white matter lesions in spinal cord, whereas they markedly increased and formed bundles in exacerbated lesions in late EAE.
In a subtype of lesions, which are mainly found in patients with acute fulminant multiple sclerosis with Balo's type concentric sclerosis and in a subset of early relapsing remitting multiple sclerosis, the initial myelin changes closely resemble those seen in white matter stroke (WMS), suggesting a hypoxia-like tissue injury.
Earlier cohorts may remit less than more recent arrivals because they may no longer have close family members in Cuba.
A high proportion of early positive histology remitted spontaneously, and 93.1% of patients had negative histology at week 12 after RT [ 17].
Twenty-two Benign (B), 26 secondary progressive (SP), and 11 early, nondisabled relapsing-remitting (RR) MS patients and 37 healthy controls (HC) underwent conventional and diffusion tensor brain MRI and, as regards MS patients, immunophenotypic and functional analysis of stimulated peripheral blood mononuclear cells (PBMC).
However, despite this expansion of remit, the early postwar period was a period of decline for the museum.
Otherwise, the high prevalence would be difficult to explain, as the PTSD should have remitted earlier.
I am pleased that the organisation now has an excellent board in place with expertise across all of our remit areas, including early years and further education".
