Sentence examples for early readout from inspiring English sources

Initially the Alzheimer's PET tests will help drug firms get an early readout on whether their experimental antiplaque drugs are working.

This, together with the development of novel computational methods suitable for the analysis and integration of very large multilevel datasets [5], have contributed to demonstrate the usefulness of molecular fingerprinting in predicting toxicity from an early readout of the response to chemical exposure [5] [9].

Targeting of these end points would aid choice of doses and schedules, and provide an early readout of potential efficacy.

Common insertion sites (CIS) are integration hotspots that may represent an early readout of insertional mutagenesis or an intrinsic bias of the vector of interest.

Pilot studies suggest that optical imaging methods (for example, diffuse optical spectroscopy) can provide an early readout of treatment efficacy [ 15], and larger, multicenter trials of optical imaging are under way.

Furthermore, in the past decade a large number of studies have provided considerable evidence that assessment of tumor glucose utilization by FDG-PET provides an early readout for the effectiveness of therapy, that it correlates with the degree of histologic tumor regression and allows prediction of patient survival.

Although we did not observe an effect of similar magnitude using an earlier readout, we show using SPICE polychromatic flow cytometry analysis that antigen-specific CD8+ T cells from mice immunised with MVA lacking B15R are composed of a higher proportion of triple-positive cells that express IL-2 in addition to IFN-γ and TNF-α.

Likewise, from a drug development perspective, earlier readouts of efficacy will improve costs and enable more nimble decision making.

Here we introduce the adult epidermis of the fly as an early onset tissue readout for the aging program.

In the clinical setting, an increase in tumour ADC, providing an early non-invasive readout of downstream induction of cell death following MEK1/2-ERK1/2 MEK1/2-ERK1/2ition in addicted cancers, would be more informative with regards to treatment outcome than molecular assessment of target modulation alone.

Such a scheme should be tested by using early TCR signalling readouts.