Given the apparently early origin of carotenoid biosynthesis, it is quite plausible that these pigments evolved originally to play a role in membrane stabilization and UV tolerance [10], [105].
It consists of two principal collections of early origin called "the proverbs of Solomon" and "proverbs of Solomon which the men of Hezekiah king of Judah copied".
Thus, many mathematical recreations of early origin that have reappeared from time to time in new dress seem to have survived chiefly because they appeal to man's sense of curiosity or mystery.
When yeast cells are stressed during S phase, Hog1 promotes gene induction and, remarkably, also delays replication by directly affecting early origin firing and fork progression.
Such cases have been termed 'developmental' [e.g. 5], [6], stressing the early origin or, 'congenital', emphasizing the absence of pathological correlate [e.g. 7], [8].
Because of their early origin within Metazoa, genomic and developmental studies of cnidarians are yielding important insights into the unfolding of animal diversity, e.g., [3] [5].
These changes were highly conserved in strains from multiple geographic locations, particularly in F.t. holarctica populations, indicating a likely early origin during subspecies divergence [12].
The close relationship of the integrases in both groups points to an early origin for this specific class of phage-related elements, probably dating from before the speciation of the Xanthomonadales.
The fossil record implies an early origin for the family; astrocoeniid-like corals with styliform and vertically continuous columella from the Middle Triassic [6] are amongst the oldest scleractinian fossils yet found.
Several of the protein import components identified in Ectocarpus, such as Tim21, Tim50 and metaxin, have also been found in other stramenopiles and this study suggests an early origin during the evolution of the eukaryotes.
For this reason such cases were labelled as "developmental" (emphasizing the early origin; note, however, that cases are subsumed under "developmental" for which an early brain damage has been reported.
