Exact(1)
In newborns, we could recently demonstrate that reduced mHLA-DR expression may reflect immunological immaturity in very early newborns [90] and a meta-analysis on GM-CSF therapy indicated increased survival rates in very-low pre-term infants (< 2000 g) and infants with neutropenia when treated with GM-CSF [91].
Similar(59)
To a large degree, this continues through early newborn life.
Perinatal outcomes (stillbirth and early newborn death) have been proposed as a facility indicator of CS quality of care [ 6].
It might be argued that the two events of infection and asphyxia act independently but additively to affect early newborn death rather than through a double-hit interaction.
NEC affects premature or early newborn infants, is characterized by transmural inflammation and intestinal necrosis, and is fatal in many cases.
These findings suggest that many asphyxiated babies, in addition to facing an hypoxic-ischaemic insult, are concurrently experiencing significant variations in blood sugars in the early newborn period.
Every year, more than a million of the world's newborns die on their first day of life; as many as two-thirds of these deaths could be saved with essential care at birth and the early newborn period.
Any potential dysmorphic or associated features should be noted and the experience of a clinical geneticist obtained early in such situations, as such signs can be subtle in the early newborn period.
During the last decades of the twentieth century the paradigm for postnatal care provision in Western countries changed and the main responsibility for early newborn care shifted to the mothers [ 15].
This puts the impact of pre-eclampsia into the same range as 3 of the 4 most important proximate causes of early newborn deaths (intrapartum complications, 27%; congenital anomalies, 10%; and sepsis, 8%, according to Lawn ).
Thus rapid diagnostic test(s) that differentiate infected from non-infected infants, particularly in the early newborn period, have the potential to make a significant impact on neonatal care.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com