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I believe consolation was one of the very early functions of music, tens of thousands of years ago.
To gain further insight into the early functions of XMeis3, we followed a gain- and a loss-of-function strategy.
The aim of our study was to define the effect of knocking down Sox2 in developing preimplantation mouse embryos, in order to uncover early functions in maintaining developmental potential of early mouse embryos and marking the pluripotent lineage [53].
To explore the functions of Otx2 in the adult eye, we took advantage of the novel genetic approach coined self-knockout that we previously used to study Otx2 early functions [18] and which allows time-controlled and very efficient knockout of Otx2 only in cells that express it.
We hypothesise that, contrary to claims of the uniquely primate nature of the specialization for face processing observed in humans (e.g. [42]), similar basic mechanisms could operate in different species due to the selective pressures shaping the early functions of the brain.
The sqt cz35 mutation selectively abolishes Sqt signaling without affecting the early functions of maternal sqt RNA or activity of other zebrafish Nodals.
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Together, the data suggest that genetic and functional redundancy interferes with RPK1's early function in Arabidopsis thaliana embryogenesis.
Its original Spanish name, Bahía de Manteca ("Butter Bay"), probably recalls its early function as a lard ("hog's butter") centre.
Minimally-invasive percutaneous calcaneoplasty can represent an alternative to open reduction internal fixation in the treatment of calcaneal fractures, allowing stable reduction without plating, early function recovery and short hospital stay.
Our targets were to (1) minimize surgical trauma by reducing complications, (2) standardize the technique, (3) avoid immobilization by encouraging early function, and (4) allow partial to full weight-bearing in 4 6 weeks.
It reduces treatment times, provides early function and aesthetics, preserves the alveolar bone as well as prevents unwanted migration of an adjacent tooth in the case of missing a single tooth.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com