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Therefore, drugs with high genetic barrier should be considered as a rescue therapy for off-treatment relapse in CHB, and early evaluation for genotypic resistance should be considered in these patients if the initial regimen shows inadequate response.
While the precise molecular mechanism has still to be elucidated, the combination of murine and pediatric OI data should make clinicians more attentive to extra-skeletal examination of OI patients and to preventive measures such as pulmonary exercise or early evaluation for nocturnal hypoxemia.
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Early evaluations for the LTE 2 × 2 MU-MIMO schemes employing various practical precoding approaches (unitary or ZF) and receiver types have disclosed gains over SU-MIMO of up to 20% only in scenarios with high transmit correlation [8].
On rare occasions, a randomised comparison might be considered unnecessary, owing to the magnitude of evidence from early evaluations (for example, the parachute scenario 21).
However, since the effect on breast cancer mortality will only become evident in the long term, monitoring the early outcomes seemed to us essential in the early phases for early evaluation of the efficacy of the screening program.
The key characteristic of the solution-focused approach is to improve the utility of risk assessment outcomes by including an early evaluation of options for reducing risks [14 16].
Data related to Potentially Preventable Complications in the Syracuse hospitals also involved early evaluation of programs for managing these outcomes that were implemented between October 2008 and March 2009.
Several novel biomarkers have recently demonstrated promise in the early evaluation of patients for sepsis and the aim of this study was to further evaluate some of the most promising in unselected patients presenting to the ICU.
This allows for an early evaluation of drug binding and for adjusting the dose to an individual patient's needs (Rathkopf et al., 2013).
The DCS was designed to close the gap between the biopharmaceutics classification system, which is aimed at guiding regulatory decisions about well-characterized drugs, and the need for early evaluation of drug candidates with respect to their suitability for oral delivery.
Furthermore, our data suggest that serum hyaluronan level is a better marker than other serum markers for early evaluation of postoperative graft function.
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