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Smoking may be related to early discontinuation of oral contraceptives (OC).
Early discontinuation of antidepressant therapy is associated with relapse and increased costs.
We aimed to assess predictors of early discontinuation of effective contraception during typical use by high-risk teens.
Reasons for early discontinuation of a trial include: evidence of benefit, evidence of harm, and evidence of futility.
Early discontinuation may lead to reduced cost-effectiveness of this method and unintended pregnancy if other contraceptives are not used.
OBJECTIVE: Patient nonadherence and early discontinuation of antidepressant treatment are common.
Predictors of early discontinuation of evidence-based medicine after acute coronary syndrome.
Loosening and early discontinuation of external fixation would mar any procedure despite being well done.
Considering current available evidence, Chiang suggests discontinuation of the overused medication with the addition of preventive medication and hopes "Studies on preventive medications plus early discontinuation vs preventive treatment alone vs early discontinuation alone are needed" [20].
Infection at the pin-site from external fixation may lead to loosening, early discontinuation of external fixation and systemic sepsis in some cases.
There were 5 serious adverse events, all considered unrelated to the study medication; the early discontinuation rate was 22.5% over the 6-month treatment period.
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