Sentence examples for early developmental time from inspiring English sources

Brain, spinal cord, and optic nerve tissues were examined from two early developmental time points (E10.5, E15.5).

This inability to generate neurospheres in response to EGF alone at early developmental time points is consistent with the rostral causal gradient of EGF-R expression as shown by Rao and colleagues [41], [42].

Such studies suggested that Xist might only be capable of triggering XCI during an early developmental time window.

Of note, Nr5a1 appears to be highly expressed in male samples from early developmental time points, whereas the other samples seem roughly similarly expressed between males and females.

This mechanism could account for the absence of elevated Cdc42 activity and concomitant increase in RhoA that we observed at the early developmental time.

Recently, two studies showed that effects of 50 mM metformin are independent of its administration during early developmental time, as positive effects on lifespan are still observed when the drug is administered at a later stage in life [ 90, 124].

The higher number of pC1 neurons labeled by the intersectional approach is likely due to flip-out of the stop cassette during early developmental time-points that might transiently express 71G01-LexA.

By contrast, DTR-mediated neuronal ablation has the advantage of being highly quantifiable, and the timing of cell killing can also be controlled to minimize potential developmental changes due to the chronic silencing or ablation of cells at early developmental times (Gosgnach et al., 2006; Crone et al., 2008; Zhang et al., 2008).

Together, these data indicate that the dynamics of Shh signaling follow an adaptation profile, increasing during early developmental times to reach a peak in e8.5 e9 embryos, then decreasing such that by e10.5 the levels of signaling in the neural tube are low.

Relatively large amorphous 'patches' were observed in the earliest developmental time points examined.

We hypothesized that a more severe phenotype might be observable at earlier developmental time points.