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Careful clinical evaluation should be performed in migraine patients in order to diagnose early cognitive dysfunction and, if available, have them treated properly.
Follow-up assessment of cognitive function of diabetic patients is recommended to detect early cognitive dysfunction, and proper glycemic control may have a good prognostic value in cognitive performance in diabetic patients.
Faster progression rates, early cognitive dysfunction or postural instability, minimal tremor or symmetry at onset may indicate a Parkinson plus disease rather than PD itself.
Activation of D1/PKA signaling pathway may have potential therapeutic effect on AD early cognitive dysfunction.
For example, selective loss of NE exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice (Hammerschmidt et al., 2013).
Development of validated tools to characterize more precisely the existence of early cognitive dysfunction is also warranted as this can imply higher risk of suffering hip fracture.
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To evaluate effect of parecoxib sodium pretreatment combined with dexmedetomidine on early postoperative cognitive dysfunction in elderly patients after shoulder arthroscopy.
To evaluate intranasal administration of butorphanol on postoperative pain and early postoperative cognitive dysfunction in old patients undergoing H-uvulopalatopharyngoplasty (H-UPPP).
With increasing numbers of elderly adults, evidence-based approaches that can help to slow or prevent cognitive decline in the early stages of cognitive dysfunction are needed (2).
In order to identify the early features of cognitive dysfunction, a cross-sectional analysis was carried out on patients with a disease duration of <3 years (n = 7).
Reduced verbal fluency and, to a lesser extent, executive functioning have been reported as the most consistent early feature of cognitive dysfunction in FTDP-17T individuals (Van Swieten et al., 1999; Ferman et al., 2003).
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